Children’s Health

Physicians have long known that necrotizing enterocolitis (NEC), a potentially lethal inflammatory condition that destroys a premature infant’s intestinal lining, is often connected to the development of severe brain injury in those infants who survive. However, the means by which the diseased intestine “communicates” its devastation to the newborn brain has remained largely unknown. Now,
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Researchers at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered a new metabolic vulnerability in a highly aggressive form of non-small cell lung cancer (NSCLC). These findings could pave the way for new treatments for patients with mutations in two key genes – KRAS and LKB1. Patients whose tumors contain both
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Reopening Florida elementary and high schools in September was followed by increased COVID-19 infections, according to data analyzed by Ben-Gurion University of the Negev, Harvard Medical School and Tel Aviv University researchers. The findings were just published in Archives of Disease in Childhood. Florida is one of the few states that provides incidence of infections
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News-Medical talks to Professor Dipanjan Pan about the development of a paper-based electrochemical sensor that can detect COVID-19 in less than five minutes.Thought LeadersProfessor Dipanjan PanProfessor, University of Maryland BaltimoreUniversity of Maryland Baltimore County What led you to begin this research? The emergence of the coronavirus disease 2019 (COVID-19) pandemic has literally changed the way
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The impact of the COVID-19 pandemic on children with disabilities has not received much attention, perhaps because the disease disproportionately affects older individuals. In this special issue of the Journal of Pediatric Rehabilitation Medicine experts assess the impact of the pandemic on pediatric patients with special needs, their caregivers, and healthcare providers. They also focus
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There has been continual progress in expanding immunization programs over time, but even before the COVID-19 pandemic, tens of millions of children worldwide were not receiving basic doses of vaccines. New research finds that there continue to be significant disparities in childhood vaccination, and poorer children from under-represented and minority groups in most countries are
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Through small, neighborhood classes, researchers at UPMC Children’s Hospital of Pittsburgh and Promundo-US significantly reduced sexual violence among teenage boys living in areas of concentrated disadvantage. The study, published today in JAMA, is the culmination of a large Centers for Disease Control and Prevention clinical trial spanning 20 racially segregated neighborhoods in the Pittsburgh area
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Pregnant women may be especially vulnerable to developing more severe cases of COVID-19 following SARS-CoV-2 infection, but little is known about their anti-SARS-CoV-2 immune response or how it may affect their offspring. In a study published in JAMA Network Open, a group led by investigators at Massachusetts General Hospital (MGH) provides new insights that could
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One of the most recognizable characteristics of autism is an amazing diversity of associated behavioral symptoms. Clinicians view autism as a broad spectrum of related disorders, and the origin of the disease’s heterogeneity has puzzled scientists, doctors, and affected families for decades. In a recent study, researchers at Columbia University Vagelos College of Physicians and
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Researchers at the Kobe University Graduate School of Medicine have revealed that alterations in fetal microglia resulting from maternal inflammation could contribute towards the onset of developmental and psychiatric disorders. The research team including PhD student OZAKI Kana and Professor YAMADA Hideto et al. from the Department of Obstetrics and Gynecology observed that infant mice
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Substances present in cooked meats are associated with increased wheezing in children, Mount Sinai researchers report. Their study, published in Thorax, highlights pro-inflammatory compounds called advanced glycation end-products (AGEs) as an example of early dietary risk factors that may have broad clinical and public health implications for the prevention of inflammatory airway disease. Asthma prevalence
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Jean Lengenfelder, PhD, of Kessler Foundation, received a two-year $168,001 grant from the New Jersey Commission on Brain Injury Research to study the impact of traumatic brain injury (TBI) on the ability of children to reliably process the emotions of others. Children with TBI often struggle with social interaction and relationships, even years after their
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COVID-19 antibodies preferentially target a different part of the virus in mild cases of COVID-19 than they do in severe cases, and wane significantly within several months of infection, according to a new study by researchers at Stanford Medicine. The findings identify new links between the course of the disease and a patient’s immune response.
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Recent analyses indicate that pregnant women and newborns may face elevated risks of developing more severe cases of COVID-19 following SARS-CoV-2 infection. New research led by investigators at Massachusetts General Hospital (MGH) and published in Cell reveals lower than expected transfer of protective SARS-CoV-2 antibodies via the placenta from mothers who are infected in the
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Giving antimalarial medicines to children monthly during the rainy season cut malaria deaths in children by 42 per cent, making a case for wide implementation in malaria-endemic African regions, a study found. In 2012, the World Health Organization (WHO) issued guidelines for implementing intermittent monthly drug administration, also known as Seasonal Malaria Chemoprevention (SMC), in
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