Children’s Health

Northwestern Medicine scientists developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which line blood vessel walls. Published in Cell Reports, this is the first time that vascular endothelial cells could be reached for genome editing, since the usual way to deliver CRISPR/Cas9 – through a virus – does not
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In a recent study published on the medRxiv* preprint server, a team of researchers tested the durability of antibodies produced by a vaccine-induced full-length severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and receptor-binding domain (RBD). They also analyzed the antibody levels targeting the SARS-CoV-2 Omicron variant of concern (VOC), in younger adolescent children.
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Infants born via uncomplicated cesarean delivery, without labor or membrane rupture before delivery and no concern for infection, should not need antibiotics at birth, according to a study by researchers at Children’s Hospital of Philadelphia (CHOP). The findings, which were published today in Pediatrics, could help clinicians tailor the use of early antibiotics in newborns.
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Scientists have worked at an unprecedented speed to develop vaccines to fight against the ongoing coronavirus disease 2019 (COVID-19) pandemic. This pandemic has been caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an RNA virus belonging to the family Coronaviridae. Study: Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents. Image Credit: NIAID Background It
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A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours -; a feat that’s nearly unheard of in standard clinical care. “A few weeks is what most clinicians call ‘rapid’ when it comes to sequencing a patient’s genome
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Toddler and young children’s mobility and motor skills – and preschool development – are closely aligned with good vision and eye health.   Professor Nicola Anstice at Flinders Health2Go clinic at the Sturt Campus, Bedford Park. Image Credit: Flinders University Now international experts in vision and neonatal development have found that the presence of astigmatism
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Metabolic differences could explain why some metastatic breast cancer cells rapidly generate tumors after migrating from primary tumors to the brain, while others linger for months or years before forming these secondary tumors, UT Southwestern scientists report in a new study. The findings, published in Cell Metabolism, highlight metabolic vulnerabilities in malignant cells that could
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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is undergoing repeated and extensive mutational changes that have led to the emergence of several variants of concern (VOC) that often show higher transmissibility and immune-evasion characteristics. Among these VOCs include the Delta variant, which played a major role in the most recent wave of infections, hospitalizations,
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Children conceived through medically assisted reproduction are more likely to be born premature and are at greater risk of being born small than naturally conceived babies, according to new research published today by the UCL Centre for Longitudinal Studies in collaboration with the University of Utah. However, the study of almost 250,000 U.S. families finds
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Researchers at Washington University School of Medicine in St. Louis have received three grants totaling more than $6.8 million to advance research on a novel imaging system to monitor uterine contractions. The electromyometrial imaging system, called EMMI, was invented and developed at Washington University. The device allows physicians to measure, in 3D, the electrical activity
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Marijuana use among individuals who are pregnant or postpartum and living with HIV increased from 2007 to 2019, according to a Northwestern Medicine study published in JAMA Network Open. The findings mirror national trends of increased marijuana use following legalization of recreational and medical marijuana in several U.S. states, further underscoring the need for additional
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The report, published in the journal Developmental Psychology, details how researchers from the University of Surrey studied 240 primary school students aged 7 – 11 years across a period of 11 weeks. Self-regulation describes an individuals’ ability to manage and alter their emotions, behavior and cognition. Good self-regulation is associated with positive mental health benefits
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Online learning poses additional challenges to children with chronic medical conditions or special education needs, and these patients could benefit from more support from pediatric clinicians to be academically successful, according to a new opinion piece in JAMA Pediatrics released today and co-written by researchers at Kennedy Krieger Institute and Johns Hopkins Medicine. Clinicians should
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At least 2% of the total global population have been infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) at some point during the current coronavirus disease 2019 (COVID-19) pandemic and more than 200 million infants were born since the onset of the pandemic. Millions of in-utero exposures to maternal SARS-CoV-2 infection are therefore likely.
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