Pyloric Stenosis In Babies: Symptoms, Causes, And Treatment

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The narrowing of the pylorus (stomach’s opening to the intestine) is called pyloric stenosis. It occurs due to thickened pylorus muscles that prevent the movement of food from the stomach to the intestines.

This blockage may cause projectile vomiting after feeding and often result in fluid and nutrient deficiencies, leading to dehydration and weight loss. Although forceful vomiting may occur after feeding, babies with pyloric stenosis seem to be hungry all time and demand food after vomiting.

Read this post to know about the symptoms, causes, risk factors, diagnosis, treatment, and complications of pyloric stenosis in babies.

Signs And Symptoms Of Pyloric Stenosis

You may notice pyloric stenosis signs and symptoms in your baby within three to five weeks after birth. The onset of pyloric stenosis is rare in infants older than three months.

The signs and symptoms of pyloric stenosis in babies include the following(1).

  • Vomiting: Forceful vomiting that may reach several feet is seen after feeding. Some babies may have mild vomiting initially and it gradually worsens to projectile vomiting as the pylorus The vomitus consists of breastmilk or formula and rarely contains blood.
  • Abdominal contractions: A wave-like movement on the upper abdomen may occur due to stomach contractions (peristalsis). This is usually seen after feeding but before vomiting. This is due to stomach muscles trying to move food through the narrow pylorus to the intestine.
  • Hunger: Babies with pyloric stenosis may demand feeding soon after vomiting.
  • Bowel habit changes: Babies may have constipation or fewer bowel movements since less food reaches the intestines.
  • Dehydration: Vomiting may result in dehydration. Dry diapers, fewer wet diapers, crying without tears, and lethargy are the notable signs of dehydration. You must seek immediate medical care in such cases.
  • Poor weight gain: Babies with pyloric stenosis may have weight loss or poor weight gain due to inadequate absorption of nutrients.

Seek medical care if your baby has signs and symptoms of pyloric stenosis. Delaying the care may increase the risk of dehydration and lead to nutritional deficiencies.

Causes And Risk Factors For Pyloric Stenosis

Pyloric stenosis occurs due to the thickening of the pylorus, but the exact cause behind it is unknown (2). Genetic and environmental factors may be involved in the development of this anomaly. Environmental factors could play a significant role since pyloric stenosis may often not be present at birth and usually develops later.

The following factors may increase the risk for pyloric stenosis in some babies (2).

  • Male gender
  • Positive family history
  • Premature birth
  • Bottle-feeding
  • Antibiotics use, such as erythromycin, in early life
  • Maternal smoking and certain antibiotics use during pregnancy

It is not entirely known how these factors increase the risk of pyloric stenosis. Some babies with risk factors may not develop this condition.

Diagnosis Of Pyloric Stenosis

Pediatricians may be able to palpate enlarged pylorus muscle as an olive-shaped lump on the abdomen. Doctors may also ask you to feed your baby and look for abdominal contractions and projectile vomiting.

The following tests are ordered if the symptoms and signs during physical examinations are suggestive of pyloric stenosis (3).

  • Ultrasound could help visualize and examine the narrow pylorus.
  • Abdominal X-ray (barium swallow or upper GI series) are taken to confirm the diagnosis further or if the ultrasound is not clear.
  • Blood tests are also conducted to evaluate dehydration and electrolyte balance that could indicate poor absorption of nutrients.

Pediatricians may refer your baby to a pediatric gastroenterologist or a gastric surgeon to further diagnose and treat pyloric stenosis.

Treatment For Pyloric Stenosis

A surgical procedure called pyloromyotomy is required to treat pyloric stenosis. Thickened pylorus muscle is incised until the inner mucosal layer bulges out, letting the stomach contents pass to the intestines without issues. Pyoromyotomy can be done through traditional open surgery or laparoscopic surgery (4).

Intravenous fluid and electrolytes are given before surgery for dehydrated babies. Your baby may also need IV fluids for a few hours after surgery. Feeding sessions usually begin after 12 to 24 hours of surgery, and you may have to feed your baby more often to meet the nutritional needs. Some babies may have vomiting for a few days after surgery.

Complications Of Pyloric Stenosis

The possible complications of pyloric stenosis may include the following (5).

  • Dehydration and hypovolemic shock may occur due to fluid and electrolyte loss from persistent vomiting.
  • Jaundice is seen in some babies due to reduced liver enzyme levels that itself may occur due to inadequate nutrition.
  • Growth and development failure may be seen in some babies with nutritional deficiencies.
  • Stomach irritation and bleeding due to repeated vomiting may occur in some cases.

Babies usually get well and grow after the surgery (6). Bleeding and infection may happen after surgery in some babies. You may discuss with your doctor the possible surgery complications and requisite care.

Pyloric stenosis could result in life-threatening complications, such as dehydration, if left untreated. However, babies usually get better and grow normally after the procedure. A doctor may detect the condition during postnatal checkups. You may also stay alert to any signs and seek immediate medical care for timely treatment, which can help avoid any long-term problems.


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